Obesity, leptin resistance, and the effects of insulin reduction – Lustig(2004)

Lustig RH, Sen S, Soberman JE, Velasquez-Mieyer PA (2004)

Obesity, leptin resistance, and the effects of insulin reduction

Int J Obes Relat Metab Disord. 2004 Oct;28(10):1344-8.
DOI:10.1038/sj.ijo.0802753
pubmed


We reckon: This study showed in people who were leptin resistant, if you suppress insulin chemically they become leptin sensitive again – showing that chronic high levels of insulin (hyperinsulinemia) may be a cause of leptin resistance.

2 Responses to “Obesity, leptin resistance, and the effects of insulin reduction – Lustig(2004)

  • Hi 2KetoDudes,

    Thanks to Carl’s post the other week, the short videos by Robert Lustig (on Youtube) is another great way to explain Leptin Resistance (here is the link: https://www.youtube.com/watch?v=Yo3TRbkIrow).

    Cheers
    Dr Lou

    • Thanks Dr Lou – we are collecting Video resources on our site too and have Dr Lustig’s full series “The skinny on Obesity”

      //blog.2keto.com/videos/robert-lustig/the-complete-skinny-on-obesity/

      But yes episode #3 is the critical one for explaining that

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