Obesity, leptin resistance, and the effects of insulin reduction – Lustig(2004)

Lustig RH, Sen S, Soberman JE, Velasquez-Mieyer PA (2004)

Obesity, leptin resistance, and the effects of insulin reduction

Int J Obes Relat Metab Disord. 2004 Oct;28(10):1344-8.
DOI:10.1038/sj.ijo.0802753
pubmed


We reckon: This study showed in people who were leptin resistant, if you suppress insulin chemically they become leptin sensitive again – showing that chronic high levels of insulin (hyperinsulinemia) may be a cause of leptin resistance.

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